Breast implant procedures, which began in the late 1980s and became widespread after 2000, have gained such popularity that 25,000 to 30,000 people seek the treatment annually. The problem lies in side effects. Dr. Shin Dong-jin, Director of SC301 Clinic, explained, "It is reported that after 10 years of breast implant insertion, 40% of patients experience side effects such as implant rupture or leakage, shape deformation, or peri-implant contracture (tissue hardening)." He added, "If such symptoms occur, removal must be performed after confirming the detailed condition through breast ultrasound, mammogram, and MRI." He further emphasized, "Even for implant removal surgery, a doctor with about 10 years of experience must be involved to properly remove the problematic silicone." To reduce the risk of such side effects and achieve breasts with a soft texture, women primarily seek out stem cell breast augmentation.

Recently, a new procedure is being attempted in which fat is injected over the implants to add volume and eliminate the hard sensation. Dr. Shin Dong-jin stated, "Many patients visit the clinic requesting breast fat grafting over their implants one to three years after the procedure." He added, "If only fat is injected at this stage, there is a risk of necrosis, so it is advisable to incorporate stem cells. Integrating stem cells induces blood vessel formation in the fat, revitalizing it and promoting engraftment, which can help reduce the risk of capsular contracture in the tissue surrounding the implant." In this case, a higher proportion of stem cells is injected compared to standard stem cell breast augmentation to enhance cell engraftment.

Recently, there has been an increase in patients seeking to have fat and stem cells injected instead of artificial implants following breast cancer removal surgery. There has also been a growing demand for stem cell breast augmentation to restore the shape of sagging breasts after childbirth or menopause. Furthermore, it is common for patients to undergo "anti-aging surgery" at the same time as stem cell breast surgery, injecting fat and stem cells into sagging or sunken areas of the face to create a firm and three-dimensional appearance. Dr. Shin Dong-jin explained, "Injecting stem cells into the face revitalizes the skin's blood vessels, brightens the skin tone, and smooths rough textures, allowing patients to expect an anti-aging effect."

After middle age, many people seek stem cell therapy or injections to resolve pain and menopausal symptoms. Director Shin explained, “Pain is caused by various factors, such as inflammation, compression, and microscopic cracks in nerves, cartilage, muscles, and tendons.” He added, “In particular, after menopause, men complain of muscle weakness, decreased libido, and lethargy, while women suffer from hot flashes, depression, vaginal dryness, and dull skin.” He continued, “In such cases, intravenous injection of stem cell concentrate can be expected to provide benefits such as boosting immunity, improving skin health, relieving pain, enhancing sexual function, and preventing hair loss.”