From overall side effect rates to extremely rare cases of blindness and stroke—we have compiled safety data for fat grafting and SVF procedures.
SC301 Member · Trend Briefing Series · Synthesis of Multiple Studies · Purpose of Information Provision
📄 The materials covered in this briefing
Complications of facial autologous fat grafting. Plast Aesthet Res. 2024 · Moellhoff N, et al. Arterial embolism after facial fat grafting: a systematic literature review. Aesthetic Plast Surg. 2023 · Cerebral Complications Following Facial Autologous Fat Graft Injection: A Systematic Review and Meta-analysis. 2024, etc. are summarized.
4.8 %
Overall incidence of side effects (mostly mild)
3
Number of trends in this briefing
extremely rare
Frequency of serious complications such as blindness and stroke
So far, our blog has mainly focused on SVF·ADSC EffectWe introduced it focusing on... This time, changing direction, How safety data has been accumulated so farWe have summarized the following. As the purpose is to provide information, we deliver a balanced mix of good news and news to watch out for.
1
Overall stability
The overall incidence of side effects is approximately 4.8%, most of which are mild and transient.
According to literature on facial autologous fat grafting, The incidence of related side effects is reported to be approximately 4.8%, most of which are mild and temporary symptoms such as scarring, fibrosis, and edema.is. However, the research team The actual incidence rate is uncertain due to underreporting and a lack of consensus on the definition of adverse effects.It is also pointed out that...
2
Rare serious risk
The most serious complication — embolism caused by intravascular injection
The most concerning complication in fat grafting is Embolism caused by fat mistakenly entering blood vesselsis. Although extremely rare. Serious complications that can lead to blindness or strokeAccordingly, the risk is higher in areas of the face connected to blood vessels around the eyes. A recent meta-analysis synthesized case reports dealing with such cases, Summary of initial symptom patterns, including loss of consciousness, limb movement disorders, and vision lossI did.
3
Response development
Response methods for when it occurs are also evolving.
When vision loss occurs due to fat grafting, Research on emergency response methods such as intraarterial thrombolysisThis is also taking place. However, research teams commonly Once it occurs, the prognosis is not optimistic.They are reporting it, rather than a post-mortem response. Prophylactic procedure principles such as using a blunt cannula, splitting small injections, and maintaining low pressureThis is a trend that is being emphasized much more.
Summary of this briefing
fat grafting and SVF procedures Overall safety is goodMost side effects are mild and temporary. However There are extremely rare serious complications, such as embolism caused by intravascular injection.Furthermore, a common warning in this field is that once it occurs, it is not easy to respond to.
For this reason, the academic community, along with post-mortem response research Principles of prophylactic procedure (blunt cannula, fractionated injection, low-pressure injection)We are continuously emphasizing this. "How to perform the procedure safely" is just as much a core axis of research in this field as "effectiveness."
Stories from SC301 Clinic
When considering fat grafting or SVF procedures, we believe it is just as important to transparently provide safety data as it is to provide efficacy. We would appreciate it if you were aware that serious complications, while extremely rare, do exist, and that procedural principles to prevent them are continuously evolving.
SC301 Clinic examines evidence from both efficacy and safety in a balanced manner. Content faithful to providing informationI will continue.
Key Reference Materials
Complications of facial autologous fat grafting. Plast Aesthet Res. 2024; 11: 7.
Moellhoff N, Kuhlmann C, Frank K, et al. Arterial embolism after facial fat grafting: a systematic literature review. Aesthetic Plast Surg. 2023; 47: 2771-2787.
Cerebral complications following facial autologous fat graft injection: a systematic review and meta-analysis. 2024.
Wu Q, et al. Exploring superselective intraarterial thrombolysis for autologous fat injection-induced vision loss. Aesthet Surg J. 2024;44:NP337-346.
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