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Today, I have come to you with a slightly special topic.
It is using adipose stem cells (ADSCs)
Nerve reconstruction It is a story.
We commonly at plastic surgery clinics
That 'fat' you encounter when transplanting or removing fat,
Now, beyond simply cosmetic purposes
A treatment tool capable of restoring even damaged nervesIt is receiving attention.
Through the latest study by Qin et al. (2023)
ADSC actually What role it plays in nerve recovery,
I will explain it to you in detail starting now.
🧬 Adipose-derived stem cells (ADSCs), can they rebuild nerves too?!
ADSCs are adult stem cells that can be obtained from our body's adipose tissue.
It is easy to collect and has almost no rejection reaction in the body.,
It has the ability to differentiate into various organizations.
inter alia,
In that it has a function similar to Schwann cells
Innovative potential for neurological treatmentIt is showing.
In the paper, especially
peripheral nerve injuryI focused on,
ADSC reaches the damaged site
It was stated that it performs the following functions.
🧠 3 Mechanisms by which ADSCs Restore Nerves
✔ 1. Secretion of nerve growth factor
ADSC is NGF (Nerve Growth Factor), BDNF (Brain-Derived Neurotrophic Factor) Etc
secretes factors that help nerve cell survival and growth
Of the damaged area Creating a recovery environmentdo.
✔ 2. Anti-inflammatory and angiogenic effects
stem cells possess Immunomodulatory functionReduce inflammation through, and
Helps with blood vessel formation (VEGF secretion) Improve oxygen and nutrient supplyI'll do it.
✔ 3. Function similar to Schwann cells
Schwann cells are cells that surround damaged nerve axons and induce regeneration,
ADSC mimics some of these functions
An important role in nerve regenerationto do.
The two main characters active in neuroreconstruction,
Schwann cells and adipose stem cells (ADSC)!
In what ways are they similar and different?
Shall we check it out with the Seongchelin Guide?
????
🏥 How can it be utilized in actual treatment?
Then, in what cases can this be applied in plastic surgery?
✔ Promotes sensory recovery after facial nerve paralysis
✔ Support for recovery after trauma surgery for peripheral nerve damage in areas such as the jaw, ears, and eyes
✔ Helps nerve recovery in the scar area during reconstructive plastic surgery
In particular, the recovery of facial sensation
A very important psychological and functional elementis,
Nerves that were slow to recover with conventional treatment alone
With ADSC treatment, there is a possibility of faster recovery이 있습니다.
In experimental studies Group injected with ADSCis
The speed of sensory recovery is faster, and motor function recovery is also superior.They said they did it.
These results will be future Before and after plastic surgery
A system combining ADSC treatmentIt serves as a stepping stone for further development.
✨ Are there any limitations to ADSC nerve treatment?
Of course, there are still mountains to climb.
✔ Absence of standardized treatment protocols
✔ Lack of long-term safety and side effect data
✔ Stem cell (SVF) treatment cost issue
However, recently,
Tissue engineering technology combining scaffolds and ADSCsAs this develops
Methods to deliver to the precise site and increase survival rates are also being developed.
✅ What is the significance in plastic surgery practice?
ADSC goes beyond the limitations of mere 'fat grafting,'
Regenerative therapy elements that even aid in functional recoveryIt is emerging as...
✔ After surgery Patients with slow sensory recovery or concerns about nerve damageApplicable to
✔ For patients with facial nerve paralysis or traumatic injury Non-invasive recovery strategiesUseful for
Given this trend of technological advancement, before long
AI-based image diagnosis and ADSC personalized treatmentIt can also be combined!
Stem cells no longer stay only in the laboratory.
The era in which it is actually applied in plastic surgery practice,
And at the center of it Adipose-derived stem cells (ADSC)There is!
In the future, plastic surgery procedures will not only...
Functional recovery and systemic treatmentConsidering up to
The Era of Integrative TherapyI will move forward.
Dear members of the Seongchelin Family,
If you found this post helpful, please give it a like!
And regarding stem cell (SVF) therapy or research
If you have any questions, please leave them in the comments 🙂
Then, the Seongchelin manager
I'll be back with better and more informative posts!
Paper Source:
Qin, C., Zhang, Y., Zhang, Y., Zhang, H., & Liu, Y. (2023). An Update on Adipose‐Derived Stem Cells for Regenerative Medicine: Where Challenge Meets Opportunity. Stem Cells Translational Medicine, 12(4), 320–334. https://doi.org/10.1093/stcltm/szad004
#AdiposeStemCells #ADSCTherapy #PlasticSurgeryReconstruction #NerveReconstruction #PeripheralNerveInjury #FacialNerveParalysis #StemCellSVFTherapy #PlasticSurgeryTrends #StemCellResearch #StemCellTechnology #PlasticSurgeryInfo #ReconstructiveSurgery #SchwannCells #NGF #BDNF #Anti-inflammatoryTreatment #PlasticSurgeryRootCanalTreatment #TissueEngineering #PlasticSurgeryRecovery #StemCellClinicals #BioHealthcare #RegenerativeMedicine #PlasticSurgeryCases #PlasticSurgeryTips #ADSCMechanism #PlasticSurgeryKnowledge #PostoperativeSensoryRecovery #StemCellBlog #PlasticSurgeryBlog #PlasticSurgeryTrends2025
Frequently Asked Questions
🏥 How can it be utilized in actual treatment?
Then, in what cases can this be applied in plastic surgery? ✔ Promoting sensory recovery after facial nerve paralysis ✔ Supporting recovery after traumatic surgery involving damage to peripheral nerves in areas such as the jaw, ears, and around the eyes ✔ Assisting in nerve recovery in scarred areas during reconstructive plastic surgery. In particular, the recovery of facial sensation is a very important factor both psychologically and functionally,
✨ Are there any limitations to ADSC nerve treatment?
Of course, there are still hurdles to overcome. ✔ Lack of standardized treatment protocols ✔ Insufficient data on long-term safety and side effects ✔ Cost issues regarding stem cell (SVF) therapy. However, recently, with the advancement of tissue engineering technology combining scaffolds and ADSCs, methods to deliver to precise sites and increase survival rates are also being developed.
✅ What is the significance in plastic surgery practice?
ADSC is emerging as a regenerative treatment that goes beyond the limitations of mere 'fat grafting' to aid in functional recovery. ✔ Applicable to patients with slow sensory recovery after surgery or concerns regarding nerve damage ✔ Useful as a non-invasive recovery strategy for patients with facial nerve paralysis or traumatic injuries. Given this trend of technological advancement, before long
