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Can under-eye aging be changed with just one SVF session?

By 2026-05-15No Comments

Elasticity and wrinkles· Actual clinical research that simultaneously improved even dark circles

The area under the eyes is the first part of the face to reveal one's age.

It is a part.

Because the skin is thin and the fat layer is thin, even small changes

It's easily revealed.

Fine wrinkles appear, and skin elasticity decreases,

The reason why dark circles and hollowness appear together

It is right here.

Recently, this under-eye aging simply

Not the “method of filling,” but the skin itself

Attempting to improve through a regenerative approach

The research is attracting attention.

At the center of it is precisely SVF (Stromal Vascular Fraction)

.

In this article, Mae Fah Luang University in Thailand

Announced by the Department of Anti-Aging and Regenerative Medicine

Based on actual prospective clinical studies,

What changes does SVF make to the skin under the eyes?

I will summarize whether I made it.

Reference Paper:

Pattayadeekul T, Pawcsuntorn T, Nararatwanchai T.

The efficacy and safety of autologous stromal vascular fraction transplantation for infraorbital skin rejuvenation: A clinical prospective study

J Cosmet Dermatol. 2022;21(1):220–226.


Why does aging under the eyes progress particularly quickly?




The skin under the eyes is one of the thinnest parts of the face.

It is one.

When collagen and elastin decrease, the first thing

It is also a place where change is revealed.

The representative changes are as follows.

● Increase in fine lines

● Decreased skin elasticity

● Dark circles and pigmentation

● Skin atrophy and hollowing

Especially under the eyes, it is not just a simple reduction in volume,

Because the aging of the skin structure itself proceeds simultaneously

There are limitations with ordinary fillers or cosmetics alone.

It exists.


The key question the research team wanted to confirm

When SVF was transplanted under the eyes just once,

Elasticity and wrinkles· Pigmentation changes are actually improved and

"Can that effect be sustained?"

To verify this, the research team... 19 people

Close follow-up observation of patients for 6 months

We proceeded.


How was the research conducted?



Research Overview:

● Research Institution: Department of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Thailand

● Subjects: 19 adults with under-eye aging

● Age: 25–60

● Research Method: Prospective clinical study

● Tracking period: 6 months

Procedure:

1. Extract a small amount of abdominal fat.

2. Separation of SVF using an automated enzyme system

3. Direct grafting under both eyes

4. 3-month and 6-month follow-up observation


'Precise instrument analysis' rather than simple photo comparison

The reason this study is meaningful is

Not a simple visual evaluation,

The point is that it quantified the actual skin condition.

Skin Wrinkle Analysis:

By precisely measuring wrinkle depth and density, fine wrinkle changes

확인

Melanin Analysis:

Quantifying the degree of dark circles and pigmentation

Skin elasticity measurement:

The degree to which the skin stretches and then restores

Analyze and evaluate elasticity

Measurement of blood vessel condition:

Analysis of skin vascular changes and flushing conditions


Check actual results

1. Increase skin elasticity

Skin elasticity significantly improved starting from the 3-month mark

It increased and remained stable until the 6-month mark.

2. Reduction of fine lines under the eyes

Wrinkle depth and density decreased,

The effect lasted for up to 6 months.

Especially due to the characteristics of the thin and dry skin under the eyes,

Restoring elasticity itself is wrinkle improvement

It is interpreted as being connected.

3. Reduction of dark circles and melanin

Among the most interesting parts of this study

It is one.

Cases where improvement is difficult even with laser or whitening treatments

In many pigmentation problems, the melanin index

It decreased significantly.

The research team [influenced] the melanin production process

He mentioned the possibility of giving.

4. Safety

Severe in the entire study population

No side effects were reported.

However, the research team also has the following

The limitations were clearly stated.

● Small number of subjects

● Absence of control group

● Lack of long-term tracking

In other words, it is very interesting initial data, but in the future

There is a need for larger-scale randomized controlled studies.

It is the meaning.


The key mechanism by which SVF acts on the skin



Induces collagen and elastin regeneration

Improvement of skin elasticity structure through fibroblast activation

Inhibition of melanin production

Possibility of reducing hyperpigmentation

Promotion of angiogenesis

Improve the skin's oxygen and nutrient supply environment

anti-inflammatory action

Alleviation of a chronic low-inflammation environment


How is it different from fillers and Botox?

Fillers add volume,

Botox controls muscle movement.

On the other hand, SVF is The internal environment of the skin itself

It is closer to a replay approach.

In other words, not simply a “covering procedure,”

● Collagen reduction

● Loss of elasticity

● Changes in pigmentation

● Tissue atrophy

to the same cause of aging itself

The point that it is a concept intended to be approached

This is the differentiating factor.



This paper [shows] with only a single SVF transplant

Increased skin elasticity, reduced wrinkles, and reduced melanin

The possibility that it may appear simultaneously

I showed it.

Complex aging progresses, especially under the eyes

In the area Regeneration-based skin careof

It is meaningful in that it demonstrated potential.