Stem cellsMany of you might have found that somehow difficult and distant, right? But actually, our body's fat layer also has something surprisingly special. cellIt is hidden.
as soon as ADSC(Adipose-Derived Stem Cell), that is, fat-derived cells. Today, this ADSCI will easily and comfortably introduce why it is receiving attention in various fields, what characteristics it possesses, and how it differs from SVF.
ADSC, 'special cells' found in fat
ADSCis capable of being isolated from adipose tissue cellIt has the characteristic of being able to grow in various forms depending on the environment.
Thanks to this
✔ Plastic Surgery ✔ Regenerative Medicine Research ✔ Tissue Recovery Research
It is being actively utilized in various fields, such as [etc.].
When did ADSC start receiving attention?
To briefly explain the background, derived from bone marrow Mesenchymal stem cells After the multipotential ability of MSCs was first reported in academia, research continued in the 2000s showing the existence of cells with similar characteristics in adipose tissue, ADSCIt started to receive attention.
The fact that fat is relatively easy to harvest and yields a large amount of cells also makes it highly accessible as a research material. ADSC ResearchIt is cited as one of the reasons for the increased activity.
ADSC's 3 'Transformation Abilities'
ADSCHow versatile is, representative Three changesI have briefly summarized it.
① Grows into fat cells Under specific conditions, small fat droplets form and transform into a form similar to fat cells. For this reason, ADSCs are frequently receiving attention in research related to fat grafting.
② Changes in the direction of bone cells Under different conditions, it can also be observed growing in a form similar to hard bone tissue. This is also why there is so much research on ADSC in the field of reconstruction.
③ Develops into a form similar to cartilage cells When cultured in 3D, they can form like elastic cartilage cells. This is frequently used in research on areas requiring cartilage, such as the ears, nose, and joints.
Gangnam Stem Cells
※ The changes mentioned above are research results observed under experimental conditions (specific culture environments), and not all differentiation directions can be utilized in the same way in actual clinical practice.
ADSC and SVF, Two Easily Confused Terms
In blogs or consultations ADSCand SVFMany people are confused because the terms appear together. To briefly distinguish them, they are as follows.
In other words, SVF is a mixture of various cells 'ingredient'It is close to, ADSCIt is easy to understand that it refers to specific cells contained within that material.
How will it be used in plastic surgery?
현재 ADSCIt is utilized in the field of plastic surgery and reconstruction in the following auxiliary roles.
✔ fat grafting Research on Improving the City Organizational Environment
Potential for application in the field of bone and cartilage reconstruction
✔ Wound recoveryBasic research that helps
In particular, methods that handle fat and ADSC together, such as CAL (Cell-Assisted Lipotransfer), Limitations of fat graftingIt is being discussed as one of the approaches to complement it.
SC301's Stem cell (SVF) breast augmentationIt is an approach that aligns with this research trend by utilizing adipose-derived cell components together with refined fat. SC301 is calculated based on approximately 9,000 cases Average engraftment rate 77.48%an SCI-level international academic journal Annals of Plastic SurgeryIt is listed and published. (Results may vary depending on the individual.)
Points to Note Domestically — The Boundary Between Research and Clinical Application
ADSCWhile various research results related to this are being introduced with interest, the potential observed during the research phase may differ from the actual scope of clinical application approved in Korea.
As there are legal restrictions on cell-related medical practices in Korea, it is important to receive clear guidance on the actual purpose and scope of their use at this time during consultations.
Gangnam Stem Cells
The potential of ADSC that looks even more promising in the future
Just because they are cells derived from fat does not mean their functions are limited.
ADSC is
✔ Skin ✔ Cartilage ✔ Bone
It is utilized in various organizational studies, and in the future, Recovery and regeneration centerIt is attracting attention as an important cell that will expand the possibilities of personalized medicine.
Trends in the fields of plastic surgery and regeneration are also shifting beyond simple volume enhancement to consider the natural recovery and balance of tissues. ADSC is playing a major role at the center of this trend.
Frequently Asked Questions
Q. Is it possible to regenerate or treat any disease using ADSC?
A. That is not the case. The characteristic of differentiating into various tissues has been reported through research, but its use for all therapeutic purposes has not been approved in Korea. It is best to confirm the exact scope of application through consultation.
Q. Can I experience the effects of ADSCs even if I only receive an SVF transplant?
A. Since SVF contains a mixture of various cells including ADSCs, ADSCs can also play a role in procedures utilizing SVF. However, the characteristics of cultured pure ADSCs may differ from those contained within SVF.
Q. Is ADSC research also actively being conducted in Korea?
A. While related research is ongoing at the level of basic research both domestically and internationally, the scope of its application in actual medical settings may be limited in accordance with relevant laws and regulations.
to finish
I hope that through today's content, you have come to feel a little more familiar with the fact that ADSCs are very special cells that can be obtained from fat inside our bodies, which is closer than you might think.
✔️ ADSCand SVFWhether you understood the difference
✔️ Whether the potential in the research phase and the scope of actual clinical application were accepted as distinct.
✔️ Whether you were informed of the scope of domestic regulations during the consultation regarding the procedure
Keeping these three things in mind will be helpful when you come across related information.
We will continue to bring you interesting and informative stories.
The research content regarding ADSC is an introduction based on academic materials and does not guarantee therapeutic efficacy for specific diseases or individual health conditions. The scope of medical application in Korea may be restricted in accordance with relevant laws, so please confirm accurate information through an in-person consultation.
Thank you for reading. This was the Seongchelin Guide!
Frequently Asked Questions
When did ADSC start receiving attention?
To briefly outline the background, after the pluripotency of bone marrow-derived mesenchymal stem cells (MSCs) was first reported in the academic community, ADSCs began to attract attention in the 2000s as research followed revealing the existence of cells with similar characteristics in adipose tissue. The fact that adipose tissue is relatively easy to harvest and yields a large quantity of cells makes it highly accessible as a research material, which is cited as one of the reasons for the active research on ADSCs.
How will it be used in plastic surgery?
Currently, ADSCs are being utilized in the fields of plastic surgery and reconstruction in the following auxiliary roles: ✔ Research on improving the tissue environment during fat grafting ✔ Potential applications in bone and cartilage reconstruction ✔ Basic research to aid wound healing. In particular, methods that combine fat and ADSCs, such as CAL (Cell-Assisted Lipotransfer), are being discussed as one of the approaches to complement the limitations of fat grafting.
